Who we are :

The Experimental Pulmonology and Inflammation Research (EXPIRE) group is a scientific research group housed in the Medical Biology and Pathology department in the University Medical Center Groningen (UMCG). The main research focus of the group are lung diseases: Asthma, Chronic Obstructive Pulmonary Disease (COPD) and Idiopathic Pulmonary Fibrosis (IPF). Diseased and healthy lungs are studied in our laboratory at genetic, cellular, immunological, and 3D structural levels, from childhood to old age.


Our Research ->

Latest News:


Our Latest Publications:

  • Pouwels, SD, Chen, H, Rathnayake, SNH, Lan, A, Mahbub, RM, Yeung, ACY et al.. A comprehensive multi-omics and functional study of evolutionary adaptive responses to smoke. iScience. 2026;29 (5):115547. doi: 10.1016/j.isci.2026.115547. PubMed PMID:42016314 PubMed Central PMC13092862.
  • Liu, Y, van der Ploeg, EA, Borghuis, T, Menz, RI, Timens, W, Vonk, JM et al.. A Potential Novel Molecular Interaction in Bronchiolitis Obliterans Syndrome in Lung Transplantation Patients: The Role of SERPINA3 and Osteoprotegerin. FASEB J. 2026;40 (8):e71748. doi: 10.1096/fj.202503694R. PubMed PMID:42007764 PubMed Central PMC13094457.

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