Below a list of publications found on Pubmed where members of our group where (co)author on:

  • Kruk, DMLW, Wisman, M, Noordhoek, JA, Nizamoglu, M, Jonker, MR, de Bruin, HG et al.. Paracrine Regulation of Alveolar Epithelial Damage and Repair Responses by Human Lung-Resident Mesenchymal Stromal Cells. Cells. 2021;10 (11):. doi: 10.3390/cells10112860. PubMed PMID:34831082 .
  • Pouwels, SD, Burgess, JK, Verschuuren, E, Slebos, DJ. The cellular composition of the lung lining fluid gradually changes from bronchus to alveolus. Respir Res. 2021;22 (1):285. doi: 10.1186/s12931-021-01882-x. PubMed PMID:34736473 PubMed Central PMC8570005.
  • Aliee, H, Massip, F, Qi, C, Stella de Biase, M, van Nijnatten, J, Kersten, ETG et al.. Determinants of expression of SARS-CoV-2 entry-related genes in upper and lower airways. Allergy. 2021; :. doi: 10.1111/all.15152. PubMed PMID:34698405 .
  • Klont, F, Kwiatkowski, M, Faiz, A, van den Bosch, T, Pouwels, SD, Dekker, FJ et al.. Adsorptive Microtiter Plates As Solid Supports in Affinity Purification Workflows. J Proteome Res. 2021;20 (11):5218-5221. doi: 10.1021/acs.jproteome.1c00623. PubMed PMID:34669399 PubMed Central PMC8576839.
  • Roffel, MP, Maes, T, Brandsma, CA, van den Berge, M, Vanaudenaerde, BM, Joos, GF et al.. MiR-223 is increased in lungs of patients with COPD and modulates cigarette smoke-induced pulmonary inflammation. Am J Physiol Lung Cell Mol Physiol. 2021; :. doi: 10.1152/ajplung.00252.2021. PubMed PMID:34668437 .
  • Dinesh Kumar, N, Ter Ellen, BM, Bouma, EM, Troost, B, van de Pol, DPI, van der Ende-Metselaar, HH et al.. MOXIDECTIN AND IVERMECTIN INHIBIT SARS-COV-2 REPLICATION IN VERO E6 CELLS BUT NOT IN HUMAN PRIMARY AIRWAY EPITHELIUM CELLS. Antimicrob Agents Chemother. 2021; :AAC0154321. doi: 10.1128/AAC.01543-21. PubMed PMID:34633839 .
  • Martinez-Garcia, FD, de Hilster, RHJ, Sharma, PK, Borghuis, T, Hylkema, MN, Burgess, JK et al.. Architecture and Composition Dictate Viscoelastic Properties of Organ-Derived Extracellular Matrix Hydrogels. Polymers (Basel). 2021;13 (18):. doi: 10.3390/polym13183113. PubMed PMID:34578013 PubMed Central PMC8470996.
  • Martinez-Garcia, FD, Valk, MM, Sharma, PK, Burgess, JK, Harmsen, MC. Adipose Tissue-Derived Stromal Cells Alter the Mechanical Stability and Viscoelastic Properties of Gelatine Methacryloyl Hydrogels. Int J Mol Sci. 2021;22 (18):. doi: 10.3390/ijms221810153. PubMed PMID:34576318 PubMed Central PMC8468163.
  • Waters, DW, Schuliga, M, Pathinayake, PS, Wei, L, Tan, HY, Blokland, KEC et al.. A Senescence Bystander Effect in Human Lung Fibroblasts. Biomedicines. 2021;9 (9):. doi: 10.3390/biomedicines9091162. PubMed PMID:34572347 PubMed Central PMC8470192.
  • Schuliga, M, Kanwal, A, Read, J, Blokland, KEC, Burgess, JK, Prêle, CM et al.. A cGAS-dependent response links DNA damage and senescence in alveolar epithelial cells: a potential drug target in IPF. Am J Physiol Lung Cell Mol Physiol. 2021;321 (5):L859-L871. doi: 10.1152/ajplung.00574.2020. PubMed PMID:34524912 .
  • Roffel, MP, Boudewijn, IM, van Nijnatten, JLL, Faiz, A, Vermeulen, CJ, van Oosterhout, AJ et al.. Identification of asthma associated microRNAs in bronchial biopsies. Eur Respir J. 2021; :. doi: 10.1183/13993003.01294-2021. PubMed PMID:34446467 .
  • Chen, Q, Heijink, IH, de Vries, M. Connecting GWAS Susceptibility Genes in COPD: Do We Need to Consider TGF-β2?. Am J Respir Cell Mol Biol. 2021;65 (5):468-470. doi: 10.1165/rcmb.2021-0265ED. PubMed PMID:34411507 .
  • Pouwels, SD, Hesse, L, Wu, X, Allam, VSRR, van Oldeniel, D, Bhiekharie, LJ et al.. LL-37 and HMGB1 induce alveolar damage and reduce lung tissue regeneration via RAGE. Am J Physiol Lung Cell Mol Physiol. 2021;321 (4):L641-L652. doi: 10.1152/ajplung.00138.2021. PubMed PMID:34405719 .
  • Vasse, GF, Van Os, L, De Jager, M, Jonker, MR, Borghuis, T, Van Den Toorn, LT et al.. Adipose Stromal Cell-Secretome Counteracts Profibrotic Signals From IPF Lung Matrices. Front Pharmacol. 2021;12 :669037. doi: 10.3389/fphar.2021.669037. PubMed PMID:34393771 PubMed Central PMC8355988.
  • Kuchibhotla, VNS, Starkey, MR, Reid, AT, Heijink, IH, Nawijn, MC, Hansbro, PM et al.. Inhibition of β-Catenin/CREB Binding Protein Signaling Attenuates House Dust Mite-Induced Goblet Cell Metaplasia in Mice. Front Physiol. 2021;12 :690531. doi: 10.3389/fphys.2021.690531. PubMed PMID:34385933 PubMed Central PMC8353457.
  • Ter Ellen, BM, Dinesh Kumar, N, Bouma, EM, Troost, B, van de Pol, DPI, van der Ende-Metselaar, HH et al.. Resveratrol and Pterostilbene Inhibit SARS-CoV-2 Replication in Air-Liquid Interface Cultured Human Primary Bronchial Epithelial Cells. Viruses. 2021;13 (7):. doi: 10.3390/v13071335. PubMed PMID:34372541 PubMed Central PMC8309965.
  • Roodenburg, SA, Pouwels, SD, Slebos, DJ. Airway granulation response to lung-implantable medical devices: a concise overview. Eur Respir Rev. 2021;30 (161):. doi: 10.1183/16000617.0066-2021. PubMed PMID:34348981 .
  • Weckmann, M, Bahmer, T, Bülow Sand, JM, Rank Rønnow, S, Pech, M, Vermeulen, C et al.. COL4A3 is degraded in allergic asthma and degradation predicts response to anti-IgE therapy. Eur Respir J. 2021; :. doi: 10.1183/13993003.03969-2020. PubMed PMID:34326188 .
  • Blokland, KEC, Habibie, H, Borghuis, T, Teitsma, GJ, Schuliga, M, Melgert, BN et al.. Regulation of Cellular Senescence Is Independent from Profibrotic Fibroblast-Deposited ECM. Cells. 2021;10 (7):. doi: 10.3390/cells10071628. PubMed PMID:34209854 PubMed Central PMC8307656.
  • Faiz, A, Rathnayake, SNH, Ten Hacken, NHT, Guryev, V, van den Berge, M, Pouwels, SD et al.. Single-nucleotide polymorphism rs2070600 regulates AGER splicing and the sputum levels of the COPD biomarker soluble receptor for advanced glycation end-products. ERJ Open Res. 2021;7 (2):. doi: 10.1183/23120541.00947-2020. PubMed PMID:34195255 PubMed Central PMC8236754.
  • Chen, Q, de Vries, M, Nwozor, KO, Noordhoek, JA, Brandsma, CA, Boezen, HM et al.. A Protective Role of FAM13A in Human Airway Epithelial Cells Upon Exposure to Cigarette Smoke Extract. Front Physiol. 2021;12 :690936. doi: 10.3389/fphys.2021.690936. PubMed PMID:34163376 PubMed Central PMC8215130.
  • Schiller, HB, van Breugel, M, Nawijn, MC. SARS-CoV-2-specific hotspots in virus-host interaction networks. Nat Immunol. 2021;22 (7):806-808. doi: 10.1038/s41590-021-00963-9. PubMed PMID:34155406 .
  • Faiz, A, Harkness, LM, Tjin, G, Bernal, V, Horvatovich, P, James, A et al.. Angiogenic regulatory influence of extracellular matrix deposited by resting state asthmatic and non-asthmatic airway smooth muscle cells is similar. J Cell Mol Med. 2021; :. doi: 10.1111/jcmm.16648. PubMed PMID:34146379 PubMed Central PMC8256353.
  • Nemani, SSP, Vermeulen, CJ, Pech, M, Faiz, A, Oliver, BGG, van den Berge, M et al.. COL4A3 expression in asthmatic epithelium depends on intronic methylation and ZNF263 binding. ERJ Open Res. 2021;7 (2):. doi: 10.1183/23120541.00802-2020. PubMed PMID:34109240 PubMed Central PMC8181658.
  • Schupp, JC, Adams, TS, Cosme, C Jr, Raredon, MSB, Yuan, Y, Omote, N et al.. Integrated Single-Cell Atlas of Endothelial Cells of the Human Lung. Circulation. 2021;144 (4):286-302. doi: 10.1161/CIRCULATIONAHA.120.052318. PubMed PMID:34030460 PubMed Central PMC8300155.
  • van der Ploeg, EA, Melgert, BN, Burgess, JK, Gan, CT. The potential of biomarkers of fibrosis in chronic lung allograft dysfunction. Transplant Rev (Orlando). 2021;35 (3):100626. doi: 10.1016/j.trre.2021.100626. PubMed PMID:33992914 .
  • van de Wetering, C, Elko, E, Berg, M, Schiffers, CHJ, Stylianidis, V, van den Berge, M et al.. Glutathione S-transferases and their implications in the lung diseases asthma and chronic obstructive pulmonary disease: Early life susceptibility?. Redox Biol. 2021;43 :101995. doi: 10.1016/j.redox.2021.101995. PubMed PMID:33979767 PubMed Central PMC8131726.
  • Pratte, KA, Curtis, JL, Kechris, K, Couper, D, Cho, MH, Silverman, EK et al.. Soluble receptor for advanced glycation end products (sRAGE) as a biomarker of COPD. Respir Res. 2021;22 (1):127. doi: 10.1186/s12931-021-01686-z. PubMed PMID:33906653 PubMed Central PMC8076883.
  • Koloko Ngassie, ML, Brandsma, CA, Gosens, R, Prakash, YS, Burgess, JK. The Stress of Lung Aging: Endoplasmic Reticulum and Senescence Tête-à-Tête. Physiology (Bethesda). 2021;36 (3):150-159. doi: 10.1152/physiol.00039.2020. PubMed PMID:33904785 .
  • Saikumar Jayalatha, AK, Hesse, L, Ketelaar, ME, Koppelman, GH, Nawijn, MC. The central role of IL-33/IL-1RL1 pathway in asthma: From pathogenesis to intervention. Pharmacol Ther. 2021;225 :107847. doi: 10.1016/j.pharmthera.2021.107847. PubMed PMID:33819560 .
  • Hu, S, Martinez-Garcia, FD, Moeun, BN, Burgess, JK, Harmsen, MC, Hoesli, C et al.. An immune regulatory 3D-printed alginate-pectin construct for immunoisolation of insulin producing β-cells. Mater Sci Eng C Mater Biol Appl. 2021;123 :112009. doi: 10.1016/j.msec.2021.112009. PubMed PMID:33812628 .
  • Liu, G, Philp, AM, Corte, T, Travis, MA, Schilter, H, Hansbro, NG et al.. Therapeutic targets in lung tissue remodelling and fibrosis. Pharmacol Ther. 2021;225 :107839. doi: 10.1016/j.pharmthera.2021.107839. PubMed PMID:33774068 .
  • Kruk, DMLW, Wisman, M, Bruin, HG, Lodewijk, ME, Hof, DJ, Borghuis, T et al.. Abnormalities in reparative function of lung-derived mesenchymal stromal cells in emphysema. Am J Physiol Lung Cell Mol Physiol. 2021;320 (5):L832-L844. doi: 10.1152/ajplung.00147.2020. PubMed PMID:33656381 .
  • Dwyer, DF, Ordovas-Montanes, J, Allon, SJ, Buchheit, KM, Vukovic, M, Derakhshan, T et al.. Human airway mast cells proliferate and acquire distinct inflammation-driven phenotypes during type 2 inflammation. Sci Immunol. 2021;6 (56):. doi: 10.1126/sciimmunol.abb7221. PubMed PMID:33637594 PubMed Central PMC8362933.
  • Kortekaas, RK, Burgess, JK, van Orsoy, R, Lamb, D, Webster, M, Gosens, R et al.. Therapeutic Targeting of IL-11 for Chronic Lung Disease. Trends Pharmacol Sci. 2021;42 (5):354-366. doi: 10.1016/j.tips.2021.01.007. PubMed PMID:33612289 .
  • Vasse, GF, Nizamoglu, M, Heijink, IH, Schlepütz, M, van Rijn, P, Thomas, MJ et al.. Macrophage-stroma interactions in fibrosis: biochemical, biophysical, and cellular perspectives. J Pathol. 2021;254 (4):344-357. doi: 10.1002/path.5632. PubMed PMID:33506963 PubMed Central PMC8252758.
  • Heijink, IH, Hackett, TL, Pouwels, SD. Effects of cigarette smoking on SARS-CoV-2 receptor ACE2 expression in the respiratory epithelium. J Pathol. 2021;253 (4):351-354. doi: 10.1002/path.5607. PubMed PMID:33368245 PubMed Central PMC7986690.
  • Xu, CJ, Gruzieva, O, Qi, C, Esplugues, A, Gehring, U, Bergström, A et al.. Shared DNA methylation signatures in childhood allergy: The MeDALL study. J Allergy Clin Immunol. 2021;147 (3):1031-1040. doi: 10.1016/j.jaci.2020.11.044. PubMed PMID:33338541 PubMed Central PMC8238013.
  • Ketelaar, ME, Westerlaken-van Ginkel, CD, Nawijn, MC, Ej Dubois, A, Koppelman, GH. IL-1RL1a serum levels and IL1RL1 SNPs in the prediction of food allergy. Clin Exp Allergy. 2021;51 (4):614-619. doi: 10.1111/cea.13802. PubMed PMID:33278838 PubMed Central PMC8048844.
  • Woldhuis, RR, Heijink, IH, van den Berge, M, Timens, W, Oliver, BGG, de Vries, M et al.. COPD-derived fibroblasts secrete higher levels of senescence-associated secretory phenotype proteins. Thorax. 2021;76 (5):508-511. doi: 10.1136/thoraxjnl-2020-215114. PubMed PMID:33273021 PubMed Central PMC8070616.
  • Hesse, L, van Ieperen, N, Petersen, AH, Elberink, JNGO, van Oosterhout, AJM, Nawijn, MC et al.. High dose vitamin D3 empowers effects of subcutaneous immunotherapy in a grass pollen-driven mouse model of asthma. Sci Rep. 2020;10 (1):20876. doi: 10.1038/s41598-020-77947-6. PubMed PMID:33257771 PubMed Central PMC7705678.
  • Hesse, L, Petersen, AH, Nawijn, MC. Methods for Experimental Allergen Immunotherapy: Subcutaneous and Sublingual Desensitization in Mouse Models of Allergic Asthma. Methods Mol Biol. 2021;2223 :295-335. doi: 10.1007/978-1-0716-1001-5_20. PubMed PMID:33226602 .
  • Blokland, KEC, Pouwels, SD, Schuliga, M, Knight, DA, Burgess, JK. Regulation of cellular senescence by extracellular matrix during chronic fibrotic diseases. Clin Sci (Lond). 2020;134 (20):2681-2706. doi: 10.1042/CS20190893. PubMed PMID:33084883 PubMed Central PMC7578566.
  • Pouwels, SD, Wiersma, VR, Fokkema, IE, Berg, M, Ten Hacken, NHT, van den Berge, M et al.. Acute cigarette smoke-induced eQTL affects formyl peptide receptor expression and lung function. Respirology. 2021;26 (3):233-240. doi: 10.1111/resp.13960. PubMed PMID:33078507 PubMed Central PMC7983955.
  • Faiz, A, Imkamp, K, van der Wiel, E, Boudewijn, IM, Koppelman, GH, Brandsma, CA et al.. Identifying a nasal gene expression signature associated with hyperinflation and treatment response in severe COPD. Sci Rep. 2020;10 (1):17415. doi: 10.1038/s41598-020-72551-0. PubMed PMID:33060632 PubMed Central PMC7562702.
  • Marsh, EK, Prestwich, EC, Williams, L, Hart, AR, Muir, CF, Parker, LC et al.. Pellino-1 Regulates the Responses of the Airway to Viral Infection. Front Cell Infect Microbiol. 2020;10 :456. doi: 10.3389/fcimb.2020.00456. PubMed PMID:32984077 PubMed Central PMC7488214.
  • Jiang, J, Faiz, A, Berg, M, Carpaij, OA, Vermeulen, CJ, Brouwer, S et al.. Gene signatures from scRNA-seq accurately quantify mast cells in biopsies in asthma. Clin Exp Allergy. 2020;50 (12):1428-1431. doi: 10.1111/cea.13732. PubMed PMID:32935368 PubMed Central PMC7756890.
  • Burgess, JK, Jonker, MR, Berg, M, Ten Hacken, NTH, Meyer, KB, van den Berge, M et al.. Periostin: contributor to abnormal airway epithelial function in asthma?. Eur Respir J. 2021;57 (2):. doi: 10.1183/13993003.01286-2020. PubMed PMID:32907887 .
  • Allam, VSRR, Faiz, A, Lam, M, Rathnayake, SNH, Ditz, B, Pouwels, SD et al.. RAGE and TLR4 differentially regulate airway hyperresponsiveness: Implications for COPD. Allergy. 2021;76 (4):1123-1135. doi: 10.1111/all.14563. PubMed PMID:32799375 .
  • Nawijn, MC, Timens, W. Can ACE2 expression explain SARS-CoV-2 infection of the respiratory epithelia in COVID-19?. Mol Syst Biol. 2020;16 (7):e9841. doi: 10.15252/msb.20209841. PubMed PMID:32715628 PubMed Central PMC7383087.
  • Sungnak, W, Huang, N, Bécavin, C, Berg, M, HCA Lung Biological Network. SARS-CoV-2 Entry Genes Are Most Highly Expressed in Nasal Goblet and Ciliated Cells within Human Airways. ArXiv. 2020; :. . PubMed PMID:32550242 PubMed Central PMC7280877.
  • Roffel, MP, Bracke, KR, Heijink, IH, Maes, T. miR-223: A Key Regulator in the Innate Immune Response in Asthma and COPD. Front Med (Lausanne). 2020;7 :196. doi: 10.3389/fmed.2020.00196. PubMed PMID:32509795 PubMed Central PMC7249736.
  • Hesse, L, Petersen, AH, Oude Elberink, JNG, van Oosterhout, AJM, Nawijn, MC. 1,25(OH)2VitD3 supplementation enhances suppression of grass pollen-induced allergic asthma by subcutaneous and sublingual immunotherapy in a mouse model. Sci Rep. 2020;10 (1):8960. doi: 10.1038/s41598-020-65946-6. PubMed PMID:32488022 PubMed Central PMC7265339.
  • Woldhuis, RR, de Vries, M, Timens, W, van den Berge, M, Demaria, M, Oliver, BGG et al.. Link between increased cellular senescence and extracellular matrix changes in COPD. Am J Physiol Lung Cell Mol Physiol. 2020;319 (1):L48-L60. doi: 10.1152/ajplung.00028.2020. PubMed PMID:32460521 .
  • Heijink, IH, Kuchibhotla, VNS, Roffel, MP, Maes, T, Knight, DA, Sayers, I et al.. Epithelial cell dysfunction, a major driver of asthma development. Allergy. 2020;75 (8):1902-1917. doi: 10.1111/all.14421. PubMed PMID:32460363 PubMed Central PMC7496351.
  • Osei, ET, B Mostaço-Guidolin, L, Hsieh, A, Warner, SM, Al-Fouadi, M, Wang, M et al.. Epithelial-interleukin-1 inhibits collagen formation by airway fibroblasts: Implications for asthma. Sci Rep. 2020;10 (1):8721. doi: 10.1038/s41598-020-65567-z. PubMed PMID:32457454 PubMed Central PMC7250866.
  • Ketelaar, ME, Portelli, MA, Dijk, FN, Shrine, N, Faiz, A, Vermeulen, CJ et al.. Phenotypic and functional translation of IL33 genetics in asthma. J Allergy Clin Immunol. 2021;147 (1):144-157. doi: 10.1016/j.jaci.2020.04.051. PubMed PMID:32442646 .
  • Carpaij, OA, Goorsenberg, AWM, d'Hooghe, JNS, de Bruin, DM, van den Elzen, RM, Nawijn, MC et al.. Optical Coherence Tomography Intensity Correlates with Extracellular Matrix Components in the Airway Wall. Am J Respir Crit Care Med. 2020;202 (5):762-766. doi: 10.1164/rccm.201908-1512LE. PubMed PMID:32352872 .
  • Blokland, KEC, Waters, DW, Schuliga, M, Read, J, Pouwels, SD, Grainge, CL et al.. Senescence of IPF Lung Fibroblasts Disrupt Alveolar Epithelial Cell Proliferation and Promote Migration in Wound Healing. Pharmaceutics. 2020;12 (4):. doi: 10.3390/pharmaceutics12040389. PubMed PMID:32344567 PubMed Central PMC7238173.
  • Boudewijn, IM, Roffel, MP, Vermeulen, CJ, Nawijn, MC, Kok, K, Terpstra, MM et al.. A Novel Role for Bronchial MicroRNAs and Long Noncoding RNAs in Asthma Remission. Am J Respir Crit Care Med. 2020;202 (4):614-618. doi: 10.1164/rccm.201908-1610LE. PubMed PMID:32339464 .
  • Sungnak, W, Huang, N, Bécavin, C, Berg, M, Queen, R, Litvinukova, M et al.. SARS-CoV-2 entry factors are highly expressed in nasal epithelial cells together with innate immune genes. Nat Med. 2020;26 (5):681-687. doi: 10.1038/s41591-020-0868-6. PubMed PMID:32327758 .
  • Portelli, MA, Dijk, FN, Ketelaar, ME, Shrine, N, Hankinson, J, Bhaker, S et al.. Phenotypic and functional translation of IL1RL1 locus polymorphisms in lung tissue and asthmatic airway epithelium. JCI Insight. 2020;5 (8):. doi: 10.1172/jci.insight.132446. PubMed PMID:32324168 PubMed Central PMC7205441.
  • Koopmans, T, Hesse, L, Nawijn, MC, Kumawat, K, Menzen, MH, Sophie T Bos, I et al.. Smooth-muscle-derived WNT5A augments allergen-induced airway remodelling and Th2 type inflammation. Sci Rep. 2020;10 (1):6754. doi: 10.1038/s41598-020-63741-x. PubMed PMID:32317758 PubMed Central PMC7174298.
  • Kuchibhotla, VNS, Heijink, IH. Join or Leave the Club: Jagged1 and Notch2 Dictate the Fate of Airway Epithelial Cells. Am J Respir Cell Mol Biol. 2020;63 (1):4-6. doi: 10.1165/rcmb.2020-0104ED. PubMed PMID:32228394 PubMed Central PMC7328256.
  • Ubags, ND, Baker, J, Boots, A, Costa, R, El-Merhie, N, Fabre, A et al.. ERS International Congress, Madrid, 2019: highlights from the Basic and Translational Science Assembly. ERJ Open Res. 2020;6 (1):. doi: 10.1183/23120541.00350-2019. PubMed PMID:32154289 PubMed Central PMC7049707.
  • van der Wijst, M, de Vries, DH, Groot, HE, Trynka, G, Hon, CC, Bonder, MJ et al.. The single-cell eQTLGen consortium. Elife. 2020;9 :. doi: 10.7554/eLife.52155. PubMed PMID:32149610 PubMed Central PMC7077978.
  • Ali, MK, Kim, RY, Brown, AC, Donovan, C, Vanka, KS, Mayall, JR et al.. Critical role for iron accumulation in the pathogenesis of fibrotic lung disease. J Pathol. 2020;251 (1):49-62. doi: 10.1002/path.5401. PubMed PMID:32083318 .
  • de Hilster, RHJ, Sharma, PK, Jonker, MR, White, ES, Gercama, EA, Roobeek, M et al.. Human lung extracellular matrix hydrogels resemble the stiffness and viscoelasticity of native lung tissue. Am J Physiol Lung Cell Mol Physiol. 2020;318 (4):L698-L704. doi: 10.1152/ajplung.00451.2019. PubMed PMID:32048864 PubMed Central PMC7191637.
  • Zuo, H, Trombetta-Lima, M, Heijink, IH, van der Veen, CHTJ, Hesse, L, Faber, KN et al.. A-Kinase Anchoring Proteins Diminish TGF-β1/Cigarette Smoke-Induced Epithelial-To-Mesenchymal Transition. Cells. 2020;9 (2):. doi: 10.3390/cells9020356. PubMed PMID:32028718 PubMed Central PMC7072527.
  • Kuchibhotla, VNS, Jonker, MR, de Bruin, HG, Noordhoek, JA, Knight, DA, Nawijn, MC et al.. Inhibition of β-catenin/CBP signalling improves airway epithelial barrier function and suppresses CCL20 release. Allergy. 2020;75 (7):1786-1789. doi: 10.1111/all.14216. PubMed PMID:32027380 PubMed Central PMC7383853.
  • Qi, C, Jiang, Y, Yang, IV, Forno, E, Wang, T, Vonk, JM et al.. Nasal DNA methylation profiling of asthma and rhinitis. J Allergy Clin Immunol. 2020;145 (6):1655-1663. doi: 10.1016/j.jaci.2019.12.911. PubMed PMID:31953105 PubMed Central PMC7282965.
  • Dijk, FN, Vijverberg, SJ, Hernandez-Pacheco, N, Repnik, K, Karimi, L, Mitratza, M et al.. IL1RL1 gene variations are associated with asthma exacerbations in children and adolescents using inhaled corticosteroids. Allergy. 2020;75 (4):984-989. doi: 10.1111/all.14125. PubMed PMID:31755552 PubMed Central PMC7176513.
  • Osei, ET, Brandsma, CA, Timens, W, Heijink, IH, Hackett, TL. Current perspectives on the role of interleukin-1 signalling in the pathogenesis of asthma and COPD. Eur Respir J. 2020;55 (2):. doi: 10.1183/13993003.00563-2019. PubMed PMID:31727692 .
  • Vermeulen, CJ, Xu, CJ, Vonk, JM, Ten Hacken, NHT, Timens, W, Heijink, IH et al.. Differential DNA methylation in bronchial biopsies between persistent asthma and asthma in remission. Eur Respir J. 2020;55 (2):. doi: 10.1183/13993003.01280-2019. PubMed PMID:31699840 .
  • Aghapour, M, Remels, AHV, Pouwels, SD, Bruder, D, Hiemstra, PS, Cloonan, SM et al.. Mitochondria: at the crossroads of regulating lung epithelial cell function in chronic obstructive pulmonary disease. Am J Physiol Lung Cell Mol Physiol. 2020;318 (1):L149-L164. doi: 10.1152/ajplung.00329.2019. PubMed PMID:31693390 PubMed Central PMC6985875.
  • Imkamp, K, Bernal, V, Grzegorzcyk, M, Horvatovich, P, Vermeulen, CJ, Heijink, IH et al.. Gene network approach reveals co-expression patterns in nasal and bronchial epithelium. Sci Rep. 2019;9 (1):15835. doi: 10.1038/s41598-019-50963-x. PubMed PMID:31676779 PubMed Central PMC6825243.
  • Zuo, H, Faiz, A, van den Berge, M, Mudiyanselage, SNHR, Borghuis, T, Timens, W et al.. Cigarette smoke exposure alters phosphodiesterases in human structural lung cells. Am J Physiol Lung Cell Mol Physiol. 2020;318 (1):L59-L64. doi: 10.1152/ajplung.00319.2019. PubMed PMID:31664853 .
  • Carpaij, OA, Muiser, S, Bell, AJ, Kerstjens, HAM, Galban, CJ, Fortuna, AB et al.. Assessing small airways dysfunction in asthma, asthma remission and healthy controls using particles in exhaled air. ERJ Open Res. 2019;5 (4):. doi: 10.1183/23120541.00202-2019. PubMed PMID:31649950 PubMed Central PMC6801216.
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