Brady Rae Pinchen
Resume
UMC Groningen, Pathology & Medical Biology – Post-doctoral Researcher. November 2025 – October 2028
UMC Groningen, Pathology & Medical Biology – Guest Researcher. May 2025 – October 2025
UMC Groningen, Pathology & Medical Biology – PhD. April 2021 – May 2025
From concept to application: Construction of Organ-on-Chip devices, associated incubators, and pumps. On our new Lung-on-Chip we investigated smoking & vaping as well as viral exposures and VOC collection.
~Transcriptomics, proteomics, GC- mass spec, histology, immunofluorescence, primary cell culture. Teaching, technical and academic supervision, public speaking, team management, experimental design.~
Rijksuniversiteit Groningen – Biology MSc. September 2019 – May 2021
Focusing on cellular and molecular biology with a subfocus on behavioral and systems biology.
University of Glasgow – Human Anatomy & Dissection BSc. September 2014 – May 2018
Starting with the basics of Biology & Chemistry, from the second year on we were given our own donor cadaver with aligned classes studying each of the sections of the body from toes to nose.
Research
Starting in human anatomy & dissection at the University of Glasgow, I have been committed to working on humans since the beginning of my career. After moving from Scotland to the Netherlands and completing my master’s, I was thrilled to be offered a PhD position in the EXPIRE Lab with a new supervisor developing Lung-on-Chips. The lab has a lot of staff and was primarily an in vitro lab with primary human tissue and some animal work in certain projects; my project was to be the first of their chip work.
After some years of development and the installation of new devices and collaborations to facilitate the design and production of different chips, we began utilizing unique devices to study smoke and vape, bacteria and viruses, as well as interorgan communication and on-chip breathomics. From here, the chip group was established and has now expanded from me to include two technicians and a PhD, all working on the devices I designed.
I have been appointed as the post-doc for this section of the lab on a large national consortium, Ombion, to develop a Chronic Obstructive Lung Disease (COPD) exacerbation chip model, to further understanding of a poorly understood part of the disease prognosis. As such, I am now working on introducing circulating immune cells to the epithelial airway-on-chips and stimulating them with aggravants such as viruses and vape.
Keywords: Airway-on-Chip, On-Chip Technologies, Respiratory Science, Biomedical Research, Networking & Team Building
Click on image to enlarge
One of our 2-chamber, Airway-on-Chip devices. Length 45mm, finger-tip for scale
2022 – de Cock-Hadders Stichting
2019 – “Best Question by a PhD” – NVMB Conference