Janette K. Burgess
Resume
Bachelor of Science from University of Adelaide, Australia 1990 – Majoring in Biochemistry and Microbiology & Immunology
Bachelor of Science with Honours from University of Adelaide, Australia 1991 – Under the Supervision of Dr Brian K. May in the Department of Biochemistry “Studies on Erythroid 5-Aminolevulinate Synthase Expression”
PhD in Molecular Biology from University of New South Wales, Australia 1994-1998 – Under the supervision of Prof Beng Chong, Centre for Thrombosis and Vascular Research UNSW & Department of Haematology Prince of Wales Hospital and Prof Ian Dawes, Department of Biochemistry UNSW. “Drug-Induced Thrombocytopenia: Characterisation of Antibody-Platelet Interactions”
Appointments
Professor, Extracellular Matrix in Disease Pathogenesis, University Medical Center Groningen, 1st April 2018 – continuing appointment
Rosalind Franklin Fellow, University Medical Center Groningen, Groningen Research Institute of Asthma and COPD August 2015-August 2020
Associate Professor, The University of Sydney, working in the Department of Pathology and Medical Biology, Medical Biology Section, University Medical Center Groningen Jan 2011 – June 2015, ongoing Honorary Appointment July 2015 – present
NH&MRC Career Development Fellowship (1032695) – working in the Respiratory Cellular and Molecular Biology Group, Discipline of Pharmacology, University of Sydney. Jan 2012 – July 2015
NH&MRC R. Douglas Wright Fellowship (402835), working in the Respiratory Research Group, Discipline of Pharmacology, University of Sydney. May 2006 – December 2011
NH&MRC Peter Doherty Fellowship (165722), working in the Respiratory Research Group, Department of Pharmacology, University of Sydney.Jan 2002 – May 2006
Post Doctoral Researcher Respiratory Research Group, Department of Pharmacology, University of Sydney Mar 1999 – Dec 2001
Research Assistant and then a Research Officer Centre for Thrombosis and Vascular Research, University of New South Wales Jan 1998-Feb 1999
Research Assistant Centre for Thrombosis and Vascular Research 1992-1994
Research
Janette’s research focusses on the role of the extracellular matrix (ECM) in lung pathology. She is intrigued by the changes in the tissue and airway structures of the lungs that occur during disease development and progression and wants to know if these changes are a cause or a consequence of the pathology. Working with primary human lung cells, human lung tissue samples and patient clinical information, the research seeks to characterize the changes in the ECM that occur during disease in the lungs and to understand the mechanisms that underlie these changes. By novel in vitro cell models, ex vivo human lung tissue models and advanced microscopy imaging techniques she is unraveling the complex nature of the regulation of the ECM and exploring its potential as a future target for therapeutic intervention. This research links basic science to the goals of prevention and treatment of human lung diseases that afflict millions of people worldwide.
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Rønnow, SR, Sand, JMB, Staunstrup, LM, Bahmer, T, Wegmann, M, Lunding, L et al.. A serological biomarker of type I collagen degradation is related to a more severe, high neutrophilic, obese asthma subtype. Asthma Res Pract. 2022;8 (1):2. doi: 10.1186/s40733-022-00084-6. PubMed PMID:35418159 PubMed Central PMC9006548.
Schuliga, M, Read, J, Blokland, KEC, Waters, DW, Burgess, J, Prêle, C et al.. Self DNA perpetuates IPF lung fibroblast senescence in a cGAS-dependent manner. Clin Sci (Lond). 2020;134 (7):889-905. doi: 10.1042/CS20191160. PubMed PMID:32219338 .
Search PubMedStichting AstmaBestrijding, Netherlands
“Understanding the role of lysyl oxidases in the regulation of collagen remodelling in COPD” CI Burgess 2016 €18,400
“Unravelling bronchial thermoplasty-induced changes in extracellular matrix composition with optical coherence tomography: an unmet clinical need” CI PI Bonta, AWM Goorsenberg, JK Burgess & OA Carpaij 2018 €25,000
“Epithelial and airway smooth muscle cells crosstalk during airway development: implications for asthma manifestation” CI JK Burgess, MC Nawijn & KCW Wang 2024 €35,030
ZonMW, Netherlands
3D-bioprinted airways: A new breath to replace animal models for lung disease research Meer Kennis met Minder Dieren; MKMD Module ‘Maatschappelijke partners’ 2017- Humane ziekten en proefdiervrije innovaties Dr. MN. Hylkema (Main applicant), Dr. JK. Burgess (Project leader and secretary) 1 Aug 2018 – 31 July 2021 €200,000
ADHERE – ADHEsives for Restoration of Emphysema: 09120012110016 ZonMW Open Science Call 2021 – Lead Investigator Burgess 1 June 2023 – 31 May 2028 € 766.319
NWO, Netherlands
NWO Aspasia Premieregeling 2018-2023 €200,000
Admitted 2021 American Thoracic Society Fellow
2025 The American Thoracic Society Assembly on Respiratory Structure and Function Solbert Permutt Trailblazer Award in Pulmonary Physiology and Medicine
2015 – 2020 Rosalind Franklin Fellowship, University of Groningen & European Union
2014 Lung Foundation Australia/Lizotte Family Research Award for Interstitial Pulmonary Fibrosis Research
2012 17th International Colloquium on Lung and Airways Fibrosis Young Investigator Award
2012 – 2015 National Health and Medical Research Council Career Development Fellowship Level 2
2007 The American Thoracic Society Ann Woolcock Memorial Award
2006 – 2011 National Health and Medical Research Council R. Douglas Wright Career Development Award
2005 NSW Young Tall Poppy Award Australian Institute of Political Sciences
2004 Inaugural Rebecca L Cooper Award Institute of Biomedical Sciences, University of Sydney
2004 The Denis Wade New Investigator Award (Australian Society of Clinical and Experimental Pharmacologists and Toxicologists
2003 Finalist Fresh Science. (Young Scientists presenting their research to the media during Science Week)
2003 The Ann Woolcock Young Investigator Award, The Thoracic Society of Australia and New Zealand
2002 The ASMR NSW Branch Johnson & Johnson Research Postdoctoral Prize
2001 National Health and Medical Research Council Industry Fellowship (declined in lieu of above)
2001 – 2004 National Health and Medical Research Council Peter Doherty Fellowship (deferred for 12 months)
1997 The Speywood Medal – Highly Commended, The Australasian Society of Thrombosis and Haemostasis (Young Investigator Award)
1997 The Baikie Award, Haematology Society of Australia (Young Investigator Award)
1995 The Australian Vascular Biology Society Young Investigator Award