Research
I conduct research across several areas,
with a primary focus on microfluidics. My main work involves using microfluidic
chips to identify Damage Associated Molecular Patterns (DAMPs) and to study
inter-organ communication. I am also developing a 3D circular cell culture
environment in which stents can later be inserted to simulate lung stents. In
addition to this, I have been working on the Particles in Exhaled Air (PExA)
project. In this project, particles originating from the lower lobes of the
lungs of COPD patients are collected to investigate biomarkers that may be
associated with COPD.
Keywords:Microfluidics, COPD, Lung, 3D culture, DAMPs, Lung Stents, PExA, Biomarkers
Rae, B, Bood, V, Dijk, HJ, Vasse, GF, Melgert, BN, Nagelkerke, A et al.. Interorgan Communication Between Lung and Colorectal Epithelial Cells Studied Using a Novel Multi-Organ-On-Chip System. Compr Physiol. 2025;15 (5):e70051. doi: 10.1002/cph4.70051. PubMed PMID:40948361 PubMed Central PMC12434799. Boedijono, FS, Bood, V, Eichhorn, IA, Hansbro, PM, Slebos, DJ, van den Berge, M et al.. Identification of Genetic Factors Associated With DAMP Release in COPD Patients. Arch Bronconeumol. 2024;60 (11):714-717. doi: 10.1016/j.arbres.2024.06.020. PubMed PMID:39034199 .